Accreditation is a voluntary process which may be undertaken by schools to demonstrate compliance with specific standards designed to indicate a level of education quality. Missouri College is institutionally accredited (accredited in total) by the Accrediting Commission of Career Schools of Colleges and Technology (ACCSCT), an independent accrediting agency recognized by the United States Department of Education (DOE). This indicates that Missouri College substantially meets or exceeds the stated criteria of education quality established by ACCSCT and approved by the DOE. This recognition of institutional accreditation by ACCSCT entitles Missouri College to offer Title IV Financial Assistance to students who qualify.

An additional form of accreditation that a school may undertake to obtain is a specific, individual accreditation of certain programs (programmatic accreditation). Institutional accreditation is not the same as or a substitution for programmatic accreditation. Although programmatic accreditation is not required for employment in many cases, the existence of programmatic accreditation is a further indication that a program meets the standards of the profession, and may therefore indirectly enhance employment opportunities. Also, in some cases, programmatic accreditation will allow the graduates of the accredited program to sit for some credentialing exams immediately upon graduation without any requirement of work experience.